EA confirmed shortly afterward in May that a fresh Mut 21 coins for sale game could be published later in the year (along with a new FIFA instalment). Due to the pandemic, a regular photoshoot of Lamar Jackson for the game's cover wasn't possible. Therefore, the official photographer of the team provided photographs of the participant.

It had been confirmed that the game would release on August 28 for Xbox One, PS4, and PC. EA also confirmed that Madden NFL will be coming making it the first Madden game to start on Google's cloud streaming platform. It was announced that Madden NFL 21 will be available on Xbox collection X and PS5 after in year.

EA confirmed that the game would enable updates to next-gen versions for those who have it. However, EA put restrictions for purchasing the sport, with a restricted time window and for redeeming the upgrade. Following criticism to the conclusion, EA extended the window, saying that players can update to next-gen variations at any time before the launch of Madden NFL 22.

In late May, it was announced that Madden NFL 21 will be formally unveiled using a reveal trailer on June 1. However, shortly before that, EA pushed back the game's reveal as a result of the nationwide protests at the United States following the killing of George Floyd. The game was later revealed in complete later in June. Because of Washington Redskins announcing it might be changing its name to drop the team's controversial moniker, EA announced that the team's current logo and title would be removed from Madden NFL 21 too, and would be replaced by a generic name and logo until new ones were finalized, which could subsequently be added into the game afterwards.

EA confirmed that Madden NFL 21 wouldn't feature platform multiplayer gameplay.

Instead of a single skill button, skills are performed via the analog tick. Skills can be carried out in combos and strung together, including slides, jukes, spins, and hurdles. The ability stick is used together with pass rush moves and block-sheds currently being on the right analog stick for defending as well.

Defending sees changes in various regions as well. Tackling animations are revamped, and therefore are triggered based on places, so defenders adjust their body positions and tackle based on they are on the area. Breakdown tackling has also been inserted, while dip handling has been improved. Meanwhile, the AI has also been enhanced, with resistance quarterbacks making plays buy Madden nfl 21 coins and reacting to players' actions appropriately.